Diapin®: A food supplement with diverse therapeutic potentials
نویسندگان
چکیده
Background and Aims: For many centuries herbs spices have traditionally been used to treat or manage a variety of diseases. The formulation food supplements containing single multiple is now popular. These formulations provide biochemical, pharmacological medicinal benefits due their diverse phytochemical constituents. Methods: In the present study, Diapin® – supplement Olea europaea L. leaves extract, Cinnamomum cassia (L.) J. Presl stem Nigella sativa seed oil, Cocos nucifera oil vitamin D3 dissolved in absolute ethanol was evaluated for α-amylase, α-glucosidase, acetylcholinesterase, elastase, neuraminidase, adenosine deaminase arginase inhibitory activity. Results: strongly inhibited neuraminidase (IC50 = 0.272 ± 0.007 mg/mL), while deaminase, acetylcholinesterase, elastase were moderately (with an IC50 4.562 0.052, 5.396 0.563, 5.783 0.058 6.800 0.067 mg/mL respectively). less inhibition activity on α-amylase α-glucosidase 9.593 0.582 14.010 2.280 Conclusion: activities can be attributed its opulent composition. present findings support folkloric claim having antidiabetic, anticancer, anti-inflammatory, antimicrobial, anti-ageing, immune bolstering properties, addition mitigation Alzheimer’s disease alleviation neurological dysfunction.
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ژورنال
عنوان ژورنال: Istanbul university journal of pharmacy
سال: 2022
ISSN: ['2548-0731', '2587-2087']
DOI: https://doi.org/10.26650/istanbuljpharm.2022.980682